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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK7
All Species:
14.55
Human Site:
S421
Identified Species:
24.62
UniProt:
Q13164
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13164
NP_002740.2
816
88386
S421
C
P
D
V
E
M
P
S
P
W
A
P
S
G
D
Chimpanzee
Pan troglodytes
XP_511332
494
55249
F138
I
K
K
I
P
N
A
F
D
V
V
T
N
A
K
Rhesus Macaque
Macaca mulatta
XP_001099721
816
88521
S421
C
P
D
V
E
M
P
S
P
W
A
P
S
G
D
Dog
Lupus familis
XP_546651
731
80417
E375
D
R
E
A
L
T
R
E
R
I
K
E
A
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVS8
806
87714
S421
C
P
D
V
E
M
P
S
P
W
A
P
S
G
D
Rat
Rattus norvegicus
P0C865
806
87808
S421
C
P
D
V
E
M
P
S
P
W
A
P
S
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518277
258
29416
Chicken
Gallus gallus
Frog
Xenopus laevis
P26696
361
41238
Zebra Danio
Brachydanio rerio
NP_001013469
862
94944
S433
Q
F
K
P
L
H
S
S
G
S
A
L
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780133
1079
118303
V591
S
K
P
D
P
T
P
V
S
N
V
F
L
G
L
Poplar Tree
Populus trichocarpa
XP_002302599
372
42612
G16
G
G
D
P
N
I
K
G
I
P
T
H
G
G
R
Maize
Zea mays
NP_001152745
397
44917
A41
G
M
M
E
N
I
H
A
T
L
S
H
G
G
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
A20
Q
S
S
S
K
G
V
A
T
H
G
G
S
Y
V
Baker's Yeast
Sacchar. cerevisiae
Q00772
484
55617
A128
S
G
Q
P
L
T
D
A
H
Y
Q
S
F
T
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.6
97.6
86.7
N.A.
92
92.1
N.A.
30.3
N.A.
24.1
47.3
N.A.
N.A.
N.A.
N.A.
32.7
Protein Similarity:
100
54.6
98
87.9
N.A.
93.2
93.3
N.A.
31
N.A.
32.8
59.1
N.A.
N.A.
N.A.
N.A.
46.7
P-Site Identity:
100
0
100
0
N.A.
100
100
N.A.
0
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
100
N.A.
0
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
26.2
26.1
N.A.
25.7
28.8
N.A.
Protein Similarity:
35
35
N.A.
34.6
40.5
N.A.
P-Site Identity:
13.3
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
20
26.6
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
22
0
0
36
0
8
8
0
% A
% Cys:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
36
8
0
0
8
0
8
0
0
0
0
0
29
% D
% Glu:
0
0
8
8
29
0
0
8
0
0
0
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
8
8
0
0
% F
% Gly:
15
15
0
0
0
8
0
8
8
0
8
8
15
50
0
% G
% His:
0
0
0
0
0
8
8
0
8
8
0
15
0
0
0
% H
% Ile:
8
0
0
8
0
15
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
15
15
0
8
0
8
0
0
0
8
0
0
0
8
% K
% Leu:
0
0
0
0
22
0
0
0
0
8
0
8
8
0
8
% L
% Met:
0
8
8
0
0
29
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
8
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
29
8
22
15
0
36
0
29
8
0
29
0
0
0
% P
% Gln:
15
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
15
% R
% Ser:
15
8
8
8
0
0
8
36
8
8
8
8
43
0
8
% S
% Thr:
0
0
0
0
0
22
0
0
15
0
8
8
0
8
0
% T
% Val:
0
0
0
29
0
0
8
8
0
8
15
0
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _